Meet the Doctors

J. Gregory Mayes, DDS

Dr. Greg earned his dental degree from University of North Carolina, after earning a biology degree from San Diego State University. He has taken substantial postgraduate education in cosmetic dentistry, crowns, bridges, veneers, and tooth-colored restoration using modern composite materials.

Dr. Greg recently completed a Dental Sleep Medicine mini-residency at UNC-Chapel Hill School of Dentistry. and is a member of the American Academy of Dental Sleep Medicine.

Lisa H. Mayes, DDS

Dr. Lisa is pleased to join with her husband, Dr. Greg, in offering healthy smiles to their friends and neighbors in Cary. A lifelong Carolinian, Dr. Lisa earned both her dental degree and bachelor's degree from University of North Carolina. She then went on to complete a one-year postgraduate residency program before entering private practice. Both Dr. Greg and Dr. Lisa share in raising their wonderful daughter, Kathryn.

Ike Edwards, DDS

Dr. Ike Edwards is a Cary native and lifelong patient of the practice. He shadowed Drs. Greg and Lisa Mayes as an undergraduate and worked alongside them as a dental assistant prior to dental school. Dr. Ike received a B.S. in Architectural Design from East Carolina University giving him a keen eye for esthetics and earned his DDS from UNC School of Dentistry. He is dedicated to lifelong learning and incorporating the latest technologies into the practice of dentistry. He is an Invisalign provider, offers Same-Day Crowns, and many other convenient treatments to his patients. In his free time he enjoys cooking, exercising, traveling, visiting his family farm, and trying new restaurants. Schedule your next appointment with Dr. Ike Edwards!

Limited Time Winter Specials

Offers end March 20, 2018

New uninsured patients only

New Patient
Dental Exam


SAVE $204

Includes comprehensive exam by the doctor and necessary x‑rays.

(D0150, D0274, D0330, D0220)

New Patient
Dental Cleaning


SAVE $53

A new patient exam is required. Includes a professional dental cleaning. Does not include periodontal therapy.


New Children’s
Cleaning & Exam


SAVE $241

Patients 12 and under receive a professional dental cleaning, fluoride treatment, needed x‑rays, and a comprehensive exam.

(D1120, D1206, D0274, D0150)

Video Testimonials

Recorded interviews with our patients





What Our Patients Are Saying

Provided by Dental Revolution

No Insurance? Our patients don't need it!

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Cosmetic Dentistry

Cosmetic dentistry is one of the most cost-effective ways to improve your appearance. A beautiful, bright, healthy smile can increase self confidence and overall life satisfaction. Cosmetic dentistry can encompass things such as tooth-colored fillings, dental implants, or crowns. We have many options, so please call us for a free cosmetic consultation.

Sleep Apnea Treatment

We offer effective, nonsurgical relief from sleep apnea and other sleep-related disorders — including snoring. Ask us how you can get the restful, healthy sleep you’ve been missing.
Ask us about a free sleep apnea consultation.
We can help!


Preston Dental Center - Dr. Gregory Mayes - Dr. Lisa H. Mayes - Dr. Ike Edwards

3761 NW Cary Parkway
Cary, NC 27513

Click to view map & directions

New Patient Hotline(919) 823-6967


HoursMon-Thu 7:00am – 5:00pm